Reviving grapevine massal selection in the context of climate change: A strategy for resilient vineyards in the 21st century

Modern viticulture faces a critical paradox. The widespread adoption of clonal selection in the mid-20th century successfully standardized production and reduced viral incidence through sanitization and certification, but unintentionally created a genetically simplified vineyard landscape.

Grapevine DMR6-1 DMR6-2 double mutants display constitutive systemic acquired resistance and altered gibberellin metabolism

Achieving disease resistance in grapevine (Vitis vinifera) without compromising plant growth is a significant challenge for viticulture. Astrategy to reduce susceptibility to Downy Mildew (DM) is through dual inactivation of the salicylic acid (SA) hydroxylases VviDMR6-1 and VviDMR6-2 by gene editing, which leads to elevated endogenous SAlevels and enhanced immunity.