Dietary bioactive compounds, healthy ageing, and cognition – A focus on polyphenols and the brain
Dietary polyphenols are bioactive plant-derived compounds increasingly recognised for their potential to support cognitive health across the lifespan.
The 14th edition of the In Vino Analytica Scientia (IVAS) conference will be held jointly for the first time with the 6th edition of the Wine Active Compounds (WAC 2026) conference. The event will take place from June 29 to July 3, 2026, in Dijon, France, and is organized by the UNESCO Chair “Culture and Tradition of Vine & Wine” together with the Vine and Wine University Institute – Jules Guyot of Université Bourgogne Europe.
DOI of the book :
10.58233/wac-ivas-2026
Dietary polyphenols are bioactive plant-derived compounds increasingly recognised for their potential to support cognitive health across the lifespan.
Since 25 years in France, communication about wine has too often been considered solely as an incitement to consume an alcoholic beverage.
Sulfur dioxide (SO2) has long been an effective additive in winemaking, yet its use raises health concerns for sensitive individuals.
Resveratrol (RSV), a stilbene polyphenol naturally concentrated in the grapevine and present in red wine, has long been recognized for its bioactive potential.
The health-promoting effects of wine consumption have frequently been attributed to their antioxidant constituents; however, the direct biological actions of these components on immune cells and gut microbiota remain incompletely understood.
The wine industry is experiencing a significant global decline in wine consumption. This decline is particularly marked for red wine and the industry is seeking innovations to enhance the appeal of wine.
At the end of the 19th century, with the development of the chemical industry and the arrival of sulfite products that were easy to add throughout the winemaking process, SO2 volumes tended to increase in wines.
Viticultural practices aimed at producing lower‑alcohol wines have traditionally focused on reducing sugar accumulation in grapes through canopy management techniques—such as early leaf removal or shading—which limit photosynthetic activity and delay ripening (Palliotti et al., 2014).
Among the approaches aiming to reduce our reliance on usual phytosanitary products, stimulating plant immune responses is a promising strategy.
Vineyard exposure to wildfire smoke can contaminate grapes due to the uptake of smoke-derived volatile phenols.