WAC 2022 banner
IVES 9 IVES Conference Series 9 WAC 9 WAC 2022 9 4 - WAC - Oral presentations 9 Simgi® platform as a tool for the study of wine active compounds in the  gastrointestinal tract

Simgi® platform as a tool for the study of wine active compounds in the  gastrointestinal tract

Abstract

Simgi® platform pursues the need for dynamic in vitro simulation of the human gastrointestinal tract optimized and adapted to food safety and health fields. The platform has confirmed the model’s suitability since its first’s studies with the consistency between the simulated colonic metabolism of wine polyphenols and the metabolic evolution observed with the intake of wine in human intervention studies [1]. 

Functioning under computer control of the physicochemical parameters, simgi® system is able to simulate separately or continuously the steps of gastric, intestinal digestion and colonic fermentation. In particular, this modular configuration has allowed the simulation of gastrointestinal digestions of red wine [1] or soluble grape extracts [2], and gastrointestinal survival of probiotic enological yeasts [3], as well as the evaluation of the food matrix effect when wine and its active compounds are ingested in combination with proteins, lipids or sugars. 

The physiological conditions of the ascending, transverse and descending regions of the colon are reproduced sequentially and include the human microbial intestinal community what makes able to study the interaction between gut microbiota and polyphenols. Part of simgi® simulation studies have been carried out with wine and winery by-products using healthy [2] and diabetic microbiota. Furthermore, the dynamic operation of simgi® system made it feasible to simulate a chronic intake (14 days) of a red grape pomace extract in combination with a probiotic strain of Lactobacillus plantarum, to assess the reciprocal benefits between polyphenols and probiotics on the growth and functionality of colonic microbiota [4]. Simgi® system is also an exclusive tool to carry out avant-garde products of interest in the wine industry, for example, antimicrobial silver nanoparticles [5] and microplastics which food safety is yet to be determined. Simgi® platform (www.cial.uam-csic.es/simgi/) proposes solutions to complex challenges to effectively support research and food industry development by acting as a complement and/or as a previous step to human studies, given their ethical and economic restrictions.

[1] Cueva et al., Food Res Int. 2015; 72: 149-59
[2] Gil-Sánchez et al., J Food Compost Anal. 2018; 68: 41–52  
[3] Fernández-Pacheco et al., Food Funct. 2019; 10: 4924-31
[4] Gil-Sánchez et al., Food Res Int. 2020; 129: 108790
[5] Cueva et al., Food Chem. Toxicol. 2019; 132: 110657

DOI:

Publication date: June 14, 2022

Issue: WAC 2022

Type: Article

Authors

Alba, Tamargo, Natalia, Molinero, Carolina, Cueva, Begoña, Bartolomé, Moreno-Arribas

Presenting author

Alba, Tamargo – M. Victoria, Moreno-Arribas

Institute of Food Science Research, CIAL, (CSIC-UAM), C/ Nicolás Cabrera 9.  28049, Madrid, Spain | Institute of Food Science Research, CIAL, (CSIC-UAM), C/ Nicolás Cabrera 9.  28049, Madrid, Spain | Institute of Food Science Research, CIAL, (CSIC-UAM), C/ Nicolás Cabrera 9.  28049, Madrid, Spain, M. Victoria | Institute of Food Science Research, CIAL, (CSIC-UAM), C/ Nicolás Cabrera 9.  28049, Madrid, Spain, , 

Contact the author

Keywords

wine, simgi®, gut microbiota, digestion, metabolism

Tags

IVES Conference Series | WAC 2022

Citation

Related articles…

Agronomic and qualitative behaviour of cv. Tempranillo according to three vine spacing on two different hydric-edaphic situations in the Duero river valley

The knowledge of the influence of soil conditions on the effects that different plant densities provoke in the agronomic grapevine behaviour becomes very interesting since it allows to focus the vineyard management on the optimization of the natural, hydric and human resources.

Recent advances in our understanding of the impact of climate change on wine grape production

According to the last IPCC report, the scale of recent climate changes are unprecedented over many centuries. Each of the last four decades has been successively warmer than any decade since 1850. Projections for the future foresee that temperature could reach +3.3°C to +5.7°C under the most pessimistic scenario. It is also projected that every region will face more concurrent and multiple changes in climatic impact-drivers. The frequency of extreme climate events is also likely to increase, as well as the occurrence of indirect constraints. These evolving climatic conditions are alrealdy affecting and will continue to affect the suitability of traditional wine grape production areas, but also create opportunities in new locations.

Bentonite fining in cold wines: prediction tests, reduced efficiency and possibilities to avoid additional fining treatments

Bentonite fining is widely used to prevent protein haze in white wines. Most wineries use laboratory-scale fining trials to define the appropriate amount of bentonite to be used in the cellar. Those pre-tests need to mimic as much as possible the industrial scale fining procedure to determine the exact amount of bentonite necessary for protein stability. Nevertheless it is frequent that, after fining with the recommended amount of bentonite, wines appear still unstable and need an additional fining treatment. It remains a major challenge to understand why the same wine, fined with the same dosage of the same bentonite, achieves stability in the lab, but not in the cellar.

Mapping and tracking canopy size with VitiCanopy

Understanding vineyard variability to target management strategies, apply inputs efficiently and deliver consistent grape quality to the winery is essential. However, despite inherent vineyard variability, the majority are managed as if they are uniform. VitiCanopy is a simple, grower-friendly tool for precision/digital viticulture that allows users to collect and interpret objective spatial information about vineyard performance. After four years of field and market research, an upgraded VitiCanopy has been created to achieve a more streamlined, technology-assisted vine monitoring tool that provides users with a set of superior new features, which could significantly improve the way users monitor their grapevines. These new features include:
• New user interface
• User authentication
• Batch analysis of multiple images
• Ease the learning curve through enhanced help features
• Reporting via the creation of colour maps that will allow users to assess the spatial differences in canopies within a vineyard.
Use-case examples are presented to demonstrate the quantification and mapping of vineyard variability through objective canopy measurements, ground-truthing of remotely sensed measurements, monitoring of crop conditions, implementation of disease and water management decisions as well as creating a history of each site to forecast quality. This intelligent tool allows users to manage grapevines and make informed management choices to achieve the desired production targets and remain profitable.

Zonage et caractérisation des terroirs de l’AOC Côtes-du-Rhône: exemple du bassin de Nyons-Valreas

The southern Côtes-du-Rhône vineyard shows a significant variety of ecological facets over the Lower Rhone Valley. Intending to characterize such a variety of “terroir “called vineyard situations, a spatial approach based on identification of soil landscapes has been initiated.