WAC 2022 banner
IVES 9 IVES Conference Series 9 WAC 9 WAC 2022 9 4 - WAC - Oral presentations 9 Simgi® platform as a tool for the study of wine active compounds in the  gastrointestinal tract

Simgi® platform as a tool for the study of wine active compounds in the  gastrointestinal tract

Abstract

Simgi® platform pursues the need for dynamic in vitro simulation of the human gastrointestinal tract optimized and adapted to food safety and health fields. The platform has confirmed the model’s suitability since its first’s studies with the consistency between the simulated colonic metabolism of wine polyphenols and the metabolic evolution observed with the intake of wine in human intervention studies [1]. 

Functioning under computer control of the physicochemical parameters, simgi® system is able to simulate separately or continuously the steps of gastric, intestinal digestion and colonic fermentation. In particular, this modular configuration has allowed the simulation of gastrointestinal digestions of red wine [1] or soluble grape extracts [2], and gastrointestinal survival of probiotic enological yeasts [3], as well as the evaluation of the food matrix effect when wine and its active compounds are ingested in combination with proteins, lipids or sugars. 

The physiological conditions of the ascending, transverse and descending regions of the colon are reproduced sequentially and include the human microbial intestinal community what makes able to study the interaction between gut microbiota and polyphenols. Part of simgi® simulation studies have been carried out with wine and winery by-products using healthy [2] and diabetic microbiota. Furthermore, the dynamic operation of simgi® system made it feasible to simulate a chronic intake (14 days) of a red grape pomace extract in combination with a probiotic strain of Lactobacillus plantarum, to assess the reciprocal benefits between polyphenols and probiotics on the growth and functionality of colonic microbiota [4]. Simgi® system is also an exclusive tool to carry out avant-garde products of interest in the wine industry, for example, antimicrobial silver nanoparticles [5] and microplastics which food safety is yet to be determined. Simgi® platform (www.cial.uam-csic.es/simgi/) proposes solutions to complex challenges to effectively support research and food industry development by acting as a complement and/or as a previous step to human studies, given their ethical and economic restrictions.

[1] Cueva et al., Food Res Int. 2015; 72: 149-59
[2] Gil-Sánchez et al., J Food Compost Anal. 2018; 68: 41–52  
[3] Fernández-Pacheco et al., Food Funct. 2019; 10: 4924-31
[4] Gil-Sánchez et al., Food Res Int. 2020; 129: 108790
[5] Cueva et al., Food Chem. Toxicol. 2019; 132: 110657

DOI:

Publication date: June 14, 2022

Issue: WAC 2022

Type: Article

Authors

Alba, Tamargo, Natalia, Molinero, Carolina, Cueva, Begoña, Bartolomé, Moreno-Arribas

Presenting author

Alba, Tamargo – M. Victoria, Moreno-Arribas

Institute of Food Science Research, CIAL, (CSIC-UAM), C/ Nicolás Cabrera 9.  28049, Madrid, Spain | Institute of Food Science Research, CIAL, (CSIC-UAM), C/ Nicolás Cabrera 9.  28049, Madrid, Spain | Institute of Food Science Research, CIAL, (CSIC-UAM), C/ Nicolás Cabrera 9.  28049, Madrid, Spain, M. Victoria | Institute of Food Science Research, CIAL, (CSIC-UAM), C/ Nicolás Cabrera 9.  28049, Madrid, Spain, , 

Contact the author

Keywords

wine, simgi®, gut microbiota, digestion, metabolism

Tags

IVES Conference Series | WAC 2022

Citation

Related articles…

Local adaptation tools to ensure the viticultural sustainability in a changing climate

[lwp_divi_breadcrumbs home_text="IVES" use_before_icon="on" before_icon="||divi||400" module_id="publication-ariane" _builder_version="4.19.4" _module_preset="default" module_text_align="center" module_font_size="16px" text_orientation="center"...

Extreme canopy management for vineyard adaptation to climate change: is it a good idea?

Climate change constitutes an enormous challenge for humankind and for all human activities, viticulture not being an exception. Long-term strategic changes are probably needed the most, but growers also need to deal with short-term changes: summers that are getting progressively warmer, earlier harvest dates and higher pH in musts and wines. In the last 10-15 years, a relevant corpus of research is being developed worldwide in order to evaluate to which extent extreme canopy management operations, aimed at reducing leaf area and, thus, limiting the source to sink ratio, could be useful to delay ripening. Although extreme canopy management can result in relevant delays in harvest dates, longer term studies, as well as detailed analysis of their implications on carbohydrate reserves, bud fertility and future yield are desirable before these practices can be recommended.

Towards a regional mapping of vine water status based on crowdsourcing observations

Monitoring vine water status is a major challenge for vineyard management because it influences both yield and harvest quality. It is also a challenge at the territorial scale for identifying periods of high water restriction or zones regularly impacted by water stress. This information is of major importance for defining collective strategies, anticipating harvest logistic or applying for irrigation authorisation. At this spatial scale, existing tools and methods for monitoring vine water status are few and often require strong assumptions (e.g. water balance model). This paper proposes to consider a collaborative collection of observations by winegrowers and wine industry stakeholders (crowdsourcing) as an interesting alternative. Indeed, it allows the collection of a large number of field observations while pooling the collection effort. However, the feasibility of such a project and its interest in monitoring vine water status at regional scale has never been tested.

The objective of this article is to explore the possibility of making a regional map of vine water status based on crowdsourcing observations. It is based on the study of the free mobile application ApeX-Vigne, which allows the collection of observations about vine shoot growth. This information is easy to collect and can be considered, under certain conditions, as a proxy for vine water status. This article presents the first results obtained from the nearly 18,000 observations collected by winegrowers and wine industry stakeholders during 2019, 2020 and 2021 seasons. It presents the vine shoot growth maps obtained at regional scale and their evolution over the three vintages studied. It also proposes an analysis of the factors that favoured the number of observations collected and those that favoured their quality. These results open up new perspectives for monitoring vine water status at a regional scale but above they provide references for other crowdsourcing projects in viticulture.

Evaluation of climate change impacts at the Portuguese Dão terroir over the last decades: observed effects on bioclimatic indices and grapevine phenology

In the last decades the growers of the Portuguese Dão winegrowing region (center of Portugal) are experiencing changes in climate that are influencing either grape phenology berry health and ripening. Aiming to study the relationships between climate indices (CI), seasonal weather and grapevine phenology, in this work long-term climate and phenological data collected at the experimental vineyard of the Portuguese Dão research centre between 1958 and 2019 (61 years) for the red variety Touriga Nacional, was analyzed. The trends over time for the classical temperature-based indices (Growing Season Temperature – GST -, Growing Degree Days – GDD, Huglin Index – HI and Cool Night Index – CI) presented a significantly positive slope while the Dryness Index (DI) showed a negative trend over the last 61 years. Regarding grapevine phenology, an average advance of 4.5 days per decade in the harvest day was observed throughout the last 61 years. Consequently, the weather conditions during the ripening period have changed, showing an increasing trend over time in the average temperature (higher magnitude in the maximum than in the minimum temperature) and a decrease in the accumulated rainfall. A regression analysis showed that ~50% of harvest date variability over years was explained by the temperature-based indices variability. These observed effects of climate change on bioclimatic indices and corresponding anticipation of harvest date can still be considered advantageous for the Dão terroir as it allows to achieve an optimal berry ripening before the common equinox rains and, therefore, avoid the potential negative impacts of the rainfall on berry health and composition.

First step in the preparation of a soil map of the Protected Designation of Origin Valdepeñas (Central, Spain)

This work is a first step to make a map of vineyard soils. The characterization of the soils of the Protected Designation of Origin (D.P.O.) Valdepeñas will allow to group the studied profiles according to their physico-chemical characteristics and the concentrations of most relevant chemical elements. 90 soil profiles were analysed throughout the territory and the soils were sampled and described according to FAO (2006) and classified according to and Soil Taxonomy (2014). All samples were air dried, sieved and some physico-chemical parameters were determined following standard protocols. Also, major and trace elements were analysed by X-ray fluorescence. The statistically study was made using the SPSS program. Trend maps were made using the ArcGIS program. The studied soils have the following average properties: pH, 8.3; electrical conductivity, 0,20 dS/m (low); clay, 18.8% (medium) and CaCO3, 17.1% (high). In the study for the major elements. The major elements of these soils are Si, followed by Ca and Al, with an average content of 203.7 g/kg, 105.5 g/kg and 74.0 g/kg respectively. On the other hand, 27 trace elements have been studied. Of all of them, it can be highlighted the average values of Ba (361.8 mg/kg), Sr (129.3 mg/kg), Rb (83.4 mg/kg), V (74.2 mg/kg) and Ce (70.6 mg/kg). Ba, V and Ce values are higher and the values of Sr and Rb are lower to those found in the literature. The discriminant analysis shows a percentage of grouping of 91%. The content of chemical elements together with the physico-chemical characteristics allows grouping the soils in 4 group according to their order in the classification to Soil Taxonomy; due to the importance of the Calcisols in Castilla-La Mancha, it has been decided to establish them as their own group even if they do not appear in Soil Taxonomy classification.