terclim by ICS banner
IVES 9 IVES Conference Series 9 International Congress on Grapevine and Wine Sciences 9 2ICGWS-2023 9 Grape pomace, an active ingredient at the intestinal level: Updated evidence

Grape pomace, an active ingredient at the intestinal level: Updated evidence

Abstract

Grape pomace (GP) is a winemaking by-product particularly rich in (poly)phenols and dietary fiber, which are the main active compounds responsible for its health-promoting effects. GP-derived products have been proposed to manage cardiovascular risk factors, including endothelial dysfunction, inflammation, hypertension, hyperglycemia, and obesity. Studies on the potential impact of GP on gut health are much more recent. However, it is suggested that, to some extent, this activity of GP as a cardiometabolic health-promoting ingredient would begin in the gastrointestinal tract as GP components (i.e., (poly)phenols and fiber) undergo extensive catabolism, mainly by the action of the intestinal microbiota, that gives rise to low-molecular-weight bioactive compounds that can be absorbed and utilized by the body. This work updates the scientific evidence in relation to the activities of GP in the intestinal environment. The review includes publications from 2010 onwards, sourced from main online databases. After this peer review, we have identified six main targets of potential bioactivity of GP in the gut: (i) nutrient digestion and absorption, (ii) enteroendocrine gut hormones release and satiety, (iii) gut morphology, (iv) intestinal barrier integrity, (v) intestinal inflammatory and oxidative status, and (vi) gut microbiome (see figure) [1].

Although the current state of knowledge does not clearly define a primary mechanism of action for GP at the intestinal level, it is clearly stated that GP’s overall effect reinforces gut function as a crucial first line of defense against multiple disorders.  

References:

1) Taladrid D. et al (2023) Grape pomace as a cardiometabolic health-promoting ingredient: activity in the intestinal environment. Antioxidants,12: 979, DOI 10.3390/antiox12040979

DOI:

Publication date: October 16, 2023

Issue: ICGWS 2023

Type: Poster

Authors

Diego Taladrid1, Miguel Rebollo-Hernanz1,2, Maria A. Martin-Cabrejas1,2, M. Victoria Moreno-Arribas1, Begoña Bartolomé1*

1Institute of Food Science Research (CIAL, CSIC-UAM), c/ Nicolás Cabrera, 9, Campus de Cantoblanco, 28049, Madrid, Spain

2Department of Agricultural Chemistry and Food Science, Faculty of Science, c/ Francisco Tomás y Va-liente, 7, Universidad Autónoma de Madrid, 28049, Madrid, Spain

Contact the author*

Keywords

grape pomace, (poly)phenols, dietary fiber, intestinal environment

Tags

2ICGWS | ICGWS | ICGWS 2023 | IVES Conference Series

Citation

Related articles…

Water and nutritional savings shape non-structural carbohydrates in grapevine (Vitis vinifera L.) cuttings

Global changes and sustainability challenge researchers in saving water and nutrients. The response of woody crops, which can be forced at facing more drought events during their life, is particularly important. Vitis vinifera can be an important model for its relevance in countries subjected to climate changes and its breeding, requiring cuttings plantation and strong pruning.

Model-assisted analysis of the root traits underlying RSA genotypic diversity in Vitis: a promising approach for rootstock selection?

By dissecting the root system architecture (RSA) into its underpinning components (e.g. root emission, axial growth, radial growth, branching, root direction or tropism) and identifying the relationships between them, functional-structural 3D root models are promising tools for analyzing the diversity and complexity of root system phenotypes with Genotype × Environment interactions. The model parameters are assumed to be synthetic traits, less influenced by the environment, and consequently with less polygenic architectures than the integrative RSA traits they drive. Root models can serve as a basis for in silico development of root system ideotypes by highlighting the developmental processes and parameters that most likely influence RSA fitness.

Long-lasting flavour perception of wines treated with oenological additives considering the individual PROP taste-phenotype

The use of oenological additives is becoming a common practice due to the technological and sensory properties they provide to the wines. However, the number of studies focused on the impact that these additives might induce on wine flavor perception during wine tasting is still quite scarce. The aim of this work was to evaluate the effect of three different types of common oenological additives: two oenotannins (ellagitannin and gallotannin) and a commercial preparation of yeast mannoproteins on the long-lasting flavor perception (aroma and astringency).

Bioprotection of grape must by Metschnikowia sp.: genericity and mechanism

The market trend heads to food products with less chemical inputs, including in oenology. During the winemaking process, sulfites are commonly use to avoid microbiological contamination and stabilization of the wine thanks to its antimicrobial and antioxidant activities. Nevertheless, this use is not without consequences on human health and environment, leading for example to allergic reaction and pollution. A biological alternative to these sulfites has emerges: the bioprotection.

Influence of p-Coumaric Acid and Micronutrients on Growth and 4-Ethylphenol Production by Brettanomyces bruxellensis

The wine spoilage caused by Brettanomyces bruxellensis is one of the global concerns for winemakers. Detecting the presence of B. bruxellensis using routine laboratory culture techniques becomes challenging when cells enter the viable but not culturable (VBNC) state. This study aims to investigate the impact of p-coumaric acid (a volatile phenol precursor) and micronutrients on B. bruxellensis’ culturability, viability, and volatile phenol production under sulfite stress. In red wine, exposure to a high sulfite dose (100.00 mg L-1 potassium metabisulfite) resulted in immediate cell death, followed by a recovery of culturability after two weeks.