DNA-Free genome editing confers disease resistance in grapevine

During bottle aging, many thiol compounds are involved in the expression of bouquet of great aged red wines according to the quality of the closure.1,2 Identifying thiol compounds in red wines is a challenging task due several drawbacks including, the complexity of the matrix, the low concentration of these impact compounds and the amount of wine needed.3,4
This work aims to develop a new strategy based on the functionalisation of oak wood organic extracts with H₂S, to produce new thiols, in order to mimic what can happen in red wine during bottle aging. Following this approach and through sensory analysis experiments, we demonstrated that the vanilla-like aroma of fresh oak wood was transformed into intense “meaty” nuances similar to those found in old but non oxidized red wines.

The crossings of three wild Vitis species are commonly used as rootstocks in wine production worldwide. Factors such as disease resistance and vigor are most important for their selection.
With climate change extending drought conditions and water limitations, the selection of rootstocks conferring increased tolerance to drought takes on greater importance. Therefore, identifying Vitis species with improved drought tolerance and incorporating them into breeding programs could contribute to more resilient rootstocks under water limiting conditions. Furthermore, those species serve as a valuable resource to increase genetic variability of rootstocks. We hypothesize that species native to drier habitats will exhibit superior physiological performance under drought stress.

Catechins, a subclass of flavonoids widely found in plants and plant-based foods and beverages such as wine and tea, not only exhibit significant antioxidant properties [1], as extensively documented in the literature, but can also inhibit amyloid protein aggregation [2], a key process implicated in the onset of neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and Huntington’s.

Nowadays the use of Torulaspora delbrueckii is more and more common in winemaking. However, its behavior in presence of Saccharomyces cerevisiae is not always predictable.

AIM: The aim of this work was to study the inhibitory effect of the three most frequently used wine antioxidants – sulfur dioxide, ascorbic acid and glutathione – on the kinetics of browning caused by Botrytis cinerea laccase using a grape juice synthetic model in which (-)-epicatechin was the substrate.