WAC 2022 banner
IVES 9 IVES Conference Series 9 WAC 9 WAC 2022 9 4 - WAC - Oral presentations 9 Identification and biological properties of new resveratrol derivatives formed in red wine

Identification and biological properties of new resveratrol derivatives formed in red wine

Abstract

Resveratrol is a well-known wine constituent with a wide range of activities. In wines, resveratrol can be oxidized to form various derivatives including oligomers [1]. In this study, resveratrol derivative transformation in hydroalcoholic solution was investigated by oxidative coupling using metals. De novo resveratrol derivatives were synthetized and analysed by NMR and MS experiments including new molecules. The presence of these compounds was sought in red wines using an ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC MS/MS). This work confirmed the presence of these compounds in red wines in content comparable to that of resveratrol. Finally, biological properties of these compounds were evaluated in breast cancer and macrophage cell models.

DOI:

Publication date: June 14, 2022

Issue: WAC 2022

Type: Article

Authors

Tristan Richard, Ayoub Jaa, Anne Gutiérrez Sainz,  Josep Valls Fonayet,Stéphanie Krisa, M. Begoña Ruiz-Larrea, José Ignacio Ruiz-Sanz, Tristan Richard

Presenting author

Tristan Richard – Université de Bordeaux, Œnologie EA 4577, USC 1366 INRA, INP, ISVV, 210 chemin de Leysotte, 33882 Villenave d’Ornon, France

Free Radicals and Oxidative Stress (FROS) research group of the Department of Physiology, Medicine and Nursing School, University of the Basque Country UPV/EHU, 48940-Leioa, Bizkaia, Spain. UMR 1366, Univ. Bordeaux, INRAE, Bordeaux INP, Bordeaux Science Agro, UMR OENO, ISVV, 210 chemin de Leysotte, 33882 Villenave d’Ornon, FranceINRAE, UR Œnologie, EA 4577, USC 1366, ISVV, 210 Chemin de Leysotte, F 33882 Villenave d’Ornon, France.1Université de Bordeaux, Œnologie EA 4577, USC 1366 INRA, INP, ISVV, F-33140 Villenave d’Ornon, France

Contact the author

Keywords

resveratrol, oxidative coupling, wine, biological activities

Tags

IVES Conference Series | WAC 2022

Citation

Related articles…

Valutazione dell’equilibrio vegeto-produttivo con metodiche di proximal sensing

Nel biennio 2008-2009, nell’ambito di un progetto multidisciplinare coordinato e finanziato dal Consorzio Tuscania, 4 vigneti in differenti zone della Toscana sono stati monitorati con strumenti di proximal sensing al fine di valutare la variabilità riscontrabile e ottenere delle indicazioni sulle risposte vegetative delle piante e quanti-qualitative delle produzioni.

Improved analysis of isomeric polyphenol dimers using the 4th dimension of trapped ion mobility spectrometry – mass spectrometry

Dehydrodicatechins have recently received attention as oxidation markers especially in grapes and wine. Their analysis mainly uses LC-MS/MS which is able to differentiate them from their natural isomers (dimeric procyanidins), based on specific fragments

Study and valorization of vineyards “terroirs” in the Val de Loire

Face à la concurrence mondiale, il est indispensable de s’orienter vers des vins de qualité, marqués par une typicité et une authenticité inimitables. Le terroir représente, pour une région donnée, un patrimoine unique et non reproductible, qui peut être valorisé à travers l’origine et les caractéristiques sensorielles du vin.

Under-vine cover crops in viticulture: impact of different weed management practices on weed suppression, yield and quality of grapevine cultivar Riesling

The regulation of weeds, particularly in the under-vine area of grapevines, is essential for the maintenance of grape yield and quality.

Effect of soil type on Sauvignon blanc and Cabernet-Sauvignon wine style at different localities in South Africa

The wine producing regions of South Africa are characterized by climatic diversity. The Coastal Region has a Mediterranean climate, with a mean annual rainfall of c.